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NAIST Application NoP13-10



TitleMETHOD FOR PRODUCING L-CYSTEINE
INVENTOR OHTSU, Iwao; KAWANO, Yusuke; TAKAHASHI, Sayo; FUNAHASHI, Eri; SHIROYAMA, Maeka;
Pub.NoWO2015/033849Pub Date2015/03/12
International Application NoPCT/JP2014/072567International Application Date 2014/08/28

abstractThe present invention provides a method for producing L-cysteine with high efficiency, specifically a method for producing L-cysteine by culturing a bacterium belonging to the family Enterobacteriaceae in a culture medium to produce a culture and then collecting L-cysteine from the culture. The method is characterized in that the bacterium belonging to the family Enterobacteriaceae is so modified as to overexpress at least one protein containing a sulfur transfer domain, wherein the protein is selected from the group consisting of glp E protein, yee D protein, psp E protein, sse A protein, yce A protein and sir A protein.
National Phase